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How long does levaquin stay in the system: "Levofloxacin is offered in the market as the brand names Levaquin, Cravit, and Tavanic. Levaquin is a quinolone antibiotic used in adults to treat lung, sinus, skin, and urinary tract infections caused by certain germs called bacteria. Levaquin can increase the effects of the anticoagulant warfarin. Medications will cause health effects and serious reactions when taken with Levaquin. Some medications will cause health effects and serious reactions when taken with Levaquin."