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Norvasc blocks the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. By episodes of crushing chest pain that usually results from a lack of oxygen in the heart muscle due to clogged arteries. Continue to take Amlodipine and talk to your doctor if you experience headache, insomnia, nausea, diarrhea, or constipation. The treatment and prevention of angina resulting from coronary spasm as well as from exertion. In the heart muscle due to clogged arteries. Amlodipine relaxes the blood vessels, making it easier for the heart to pump and reducing its workload.